Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular Degeneration

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Fundus Autofluorescence and RPE Lipofuscin in Age-Related Macular Degeneration

Genes that increase susceptibility to age-related macular degeneration (AMD) have been identified; however, since many individuals carrying these risk alleles do not develop disease, other contributors are involved. One additional factor, long implicated in the pathogenesis of AMD, is the lipofuscin of retinal pigment epithelium (RPE). The fluorophores that constitute RPE lipofuscin also serve ...

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Fundus Autofluorescence in Age-related Macular Degeneration

: Fundus autofluorescence (FAF) provides detailed insight into the health of the retinal pigment epithelium (RPE). This is highly valuable in age-related macular degeneration (AMD) as RPE damage is a hallmark of the disease. The purpose of this paper is to critically appraise current clinical descriptions regarding the appearance of AMD using FAF and to integrate these findings into a chair-sid...

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Ultra-widefield fundus autofluorescence in age-related macular degeneration

BACKGROUND Establish accuracy and reproducibility of subjective grading in ultra-widefield fundus autofluorescence (FAF) imaging in patients with age-related macular degeneration (AMD), and determine if an association exists between peripheral FAF abnormalities and AMD. METHODS This was a prospective, single-blinded case-control study. Patients were consecutively recruited for the study. Pati...

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Fundus autofluorescence in age-related macular degeneration Authors:

Definitions Fluorescence is the capability of absorbing light at a specific wavelength and releasing it at a longer, less energetic wavelength. This phenomenon raises an especial interest when the released radiation is found within the spectrum of visible light permitting its visualization, recording and measurement. Autofluorescence is the spontaneous fluorescence that some substances present ...

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Fundus autofluorescence in exudative age-related macular degeneration.

The aim of this study was to investigate the characteristics of fundus autofluorescence (FAF) in patients with wet (exudative) age-related macular degeneration (AMD). Color fundus photographs, fundus fluorescein angiograms, indocyanine green angiograms, and FAF images were obtained from 61 patients (72 eyes) with exudative AMD. The FAF results for different patterns of exudative AMD were compar...

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ژورنال

عنوان ژورنال: Journal of Clinical Medicine

سال: 2014

ISSN: 2077-0383

DOI: 10.3390/jcm3041302